Download Source Code or pre-deployed code from Orchard Site.
Setup at IIS, create a website and use the souce code just downloaded.
You might see following error, means your either deployed code doesn't have permission for IUser_Machine, or the folder or location is not able to access for IUser_Machine. Or your application pool is using the old .net framework version.
add IUser_Machine permission to your application folder, if you don't add the permission, you might see following errors.